With rapid change unfolding throughout the Arctic, the need for actionable Arctic science has never been greater. A warming climate is reshaping Arctic ecosystems, bringing changes such as the loss of sea ice and glaciers, thawing of permafrost, and changing snow patterns. These shifts challenge Arctic citizens who must adapt to new environmental conditions, and have significant global implications. This report identifies emerging research questions important for understanding how environmental and societal transitions will affect the Arctic and the rest of the world. It also assesses what is required to address these questions, and points to the need to translate research findings into practical information that can help guide management and policy decisions.