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Past Event

Advances in Causal Understanding for Human Health Risk-Based Decision Making

March 6-7, 2017

The National Academies of Sciences, Engineering, and Medicine
2101 Constitution Avenue Northwest
Washington, DC

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New molecular and bioinformatic approaches have advanced understanding of how molecular pathways are affected by exposure and the molecular networks involved in disease. However, these advances are often not yet deemed sufficient to establish causality for public health risk assessments; regulators still rely primarily on traditional apical endpoints, such as those endpoints observed in animal studies.


This workshop discussed the current thinking surrounding causal models, how novel approaches and tools are relevant for environmental health, and how they can be incorporated into the decision making process. Held in Washington, DC and webcast, this workshop brought together leading environmental health experts, toxicologists, statisticians, sociologists, epidemiologists, regulators and experts from other fields that utilize different data streams for establishing causality in complex systems.


Find videos and presentations from all of the workshop sessions here.


This National Academy of Sciences activity was sponsored by the National Institutes of Environmental Health Sciences (NIEHS).

Standing Committee