Tissue Chip Presentations

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Speakers from a number of fields participated in discussions and presentations over the course of our two-day event on the use of tissue chips in environmental health studies. The speaker and panelist presentations below examine the state of development and use of biological platforms, and the promises and limitations of their use in environmental health research and regulatory contexts.

Click on the talk titles below to access the the archived presentations on YouTube. Click on [PDF] to view presentation slides.

Monday, July 21, 2014

Session 1: Potential of the Tissue Chip

William Farland and John Balbus: Welcome

Ivan Rusyn: What Do We Mean by “Tissue Chip?” [PDF]

Anthony Bahinski: The Promise of the Tissue Chip [PDF]

Kyle Kolaja: Humanizing the Tissue Chip: Use of Stem Cells to Develop Biological Platforms [PDF] to be posted soon

Weihsueh Chiu: Questions and Needs in Environmental Health and Risk Assessment Communities [PDF]

Session 2: Tissue Chips: State-of-Development [Moderator: William Farland]

J. Julie Kim: Microphysiological Modeling of the Reproductive System: Implications for Toxicity Testing and Understanding Disease Pathophysiology [PDF]

Jonathan Himmelfarb: Developing a Kidney on a Chip for Clinical and Translational Research [PDF]

D. Lansing Taylor: 3-Dimensional Liver Platforms for Predicting Drug Toxicity in Humans [PDF]

Session 3: Scientific Considerations for Use of Tissue Chips in Environmental Health Research

Franziska Boess: Comparative Assessment of 3D Models for Predictive Toxicology [PDF]

Panel Discussion: Application of Tissue Chips to Environmental Health—Scientific Challenges

Lois Lehman-McKeeman: Panelist Moderator Opening Comments

Rodger Curren

Edward LeCluyse

Christie Sayes

Russell Thomas

Panel Discussion: Application of Tissue Chips to Environmental Health—Next Steps for Research

Facilitated Discussion and Closing Comments

Anthony Bahinski

Kyle Kolaja

Lois Lehman-McKeeman

Tuesday, July 22, 2014

Session 4: Use of Tissue Chip Technologies for Environmental Health Decisions: Regulatory Considerations

Joyce Tsuji: Panelist Moderator Opening Comments

Panel Discussion: Application of Tissue Chips to Environmental Health—Government Agency Perspectives

John Bucher

Weihsueh Chiu

Danilo Tagle

Frank Weichold

Panel Discussion: Application of Tissue Chips to Environmental Health—Infusing Regulatory Considerations into Research and Development

Ivan Rusyn: Closing Remarks [PDF]