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Use of Emerging Science and Technologies to Explore Epigenetic Mechanisms Underlying the Developmental Basis for Disease

July 30-31, 2009

July’s meeting presented concepts about epigenetic mechanisms and effects, explored the current regulatory paradigm for handling implicated chemicals, and identified areas of scientific controversy. The objective of the meeting was to gain understanding of what research is most needed to inform public-health decision-makers about chemicals that cause epigenetic effects. The meetingincluded regulatory perspectives and information dissemination to the broader public and clinicians. It focused on the following:

  • observations that raise concern about epigenetic changes
  • existing, emerging, and yet-unidentified tools for screening chemicals for such effects
  • the most pressing needs for research to improve the state of the science
  • implications for risk practitioners and regulatory decision-makers
  • strategies for communicating emerging conclusions to the public