Systems Biology – Informed Risk Assessment

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Systems Biology – Informed Risk Assessment
June 14-15, 2012
National Academy of Sciences Building
2101 Constitution Avenue, NW (between 21st and C Streets, NW)
Washington D.C.
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The landscape of risk assessment is changing. These changes are driven largely by phenomenal advances in molecular and systems biology, recent reports from the National Research Council, and volumes of new test data arising from theTox21 and European REACH programs. These drivers are prompting us to look anew at current efforts to advance risk assessment through systems biology data and ask how it can augment, extend, or replace traditional data. The goal for this meeting was to consider these emerging sciences in systems biology as tools to inform risk assessment and decision making and to identify what key issues must be addressed. We presented the concepts and problems of current approaches to risk assessment and discussed the direction and means of advancing using concrete examples.


Topics Included:
Looking Toward the Horizon of Risk Assessment
Advancing Current Risk Assessment with Systems Biology
• Addressing the screening, response, and application to human populations
Value of Information and Decision-making with Systems Biology Data
How to Apply Concepts to Future of Risk Assessment


Featured Speakers:
Kim Boekelheide, Professor of Medical Sciences at Brown University
Lauren Zeise, Chief of Reproductive and Cancer Hazard Assessment, California EPA
Derek Knight, Senior Scientific Advisor at European Chemicals Agency
Ila Cote, Senior Science Advisor, National Center for Environmental Assessment, EPA
Dean Jones, Professor Medicine at Emory University
Maurice Whelan, Head of Systems Toxicology, European Commission
Robert Devlin, Senior Scientist in the Environmental Public Health Division of EPA
Greg Paoli, Co-founder of Risk Sciences International