The Promise of Genome Editing Tools to Advance Environmental Health Research

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January 10-11, 2018
National Academies of Sciences, Engineering, and Medicine
Keck Center, Room 100
500 Fifth Street N.W.
Washington, D.C.



Recent scientific advances have made genome editing technologies—a suite of biological tools for making precise additions, deletions, and alterations to the DNA and RNA of living cells– more rapid, efficient, and flexible than ever before. These advances have spurred an explosion of interest in using genome editing as a research tool in the environmental health sciences. This workshop brought together experts in molecular biology, toxicology, and public health to explore opportunities for using genome editing technologies in environmental health research. Participants discussed genome editing tools such as CRISPR/Cas9 and their applications to help unravel the mechanisms through which environmental stressors affect human health, including developing models of health and disease, testing chemicals for toxicity, and determining mechanisms of toxicity.  Speakers also explored how research that leverages genome editing tools might inform different types of decisions, including for risk assessment and environmental policy.


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Workshop Organizing Committee:   Lesa Aylward, Summit Toxicology; David Gerhold, National Center for Advancing Translational Sciences; Norbert Kaminski, Michgan State University,  Shruthi Mahalingaiah, Boston University School of Medicine; Gary Miller, Emory University, Reza Rasoulpour, Dow AgroSciences, Treye Thomas, U.S. Consumer Products Safety Commission, Chrisopher Vulpe, University of Florida; Luoping Zhang, University of California, Berkeley


Staff Lead: Keegan Sawyer, Board on Life Sciences