Webinar: Current Status And Next Directions For Basic Research on Gene Drives

October 21, 2015

This webinar reviewed the current status of gene drive research and outline next directions for the field. The webinar was an information-gathering meeting for the committee in which the speakers are invited to provide input to the committee.

  • Welcome
  • Presentation by Ethan Bier (1:09)
  • Q&A with Ethan Bier and Valentino Gantz (39:38)


Ethan Bier, Professor of Biological Sciences, University of California San Diego bio

There are two primary areas of research in Dr. Bier’s lab: 1) developmental patterning, and 2) using Drosophila as model to understand human disease processes. A major goal of the research program is to exploit genome-wide information to understand how gene regulatory networks form and function. One key component of this latter effort is to use Drosophila as a tool for identifying and characterizing the function of human genes and the disease-causing mechanisms of human bacterial pathogens. As one enabling tool in these efforts, he has developed a highly sensitive method for multiplex in situ hybridization, which makes it possible to determine the relative expression patterns of large numbers of genes with great spatial and temporal resolution.

Valentino Gantz, Post Doctoral Researcher, University of California San Diego bio

Dr. Bier is a postdoctoral researcher in the laboratory of Dr. Ethan Bier at UC San Diego. As a doctoral student, Dr. Bier lead the research to develop a mutagenic chain reaction method to copy an engineered gene from one chromosome to its counterpart using CRISPR/Cas9 genome editing system.