Reproducibility Issues in Research with Animals and Animal Models

Click here to view the presentations that were given at the workshop, as well as the video recording of the event.

Click here to view the final agenda.

Statement of Task:
An ad hoc committee will organize and conduct a public workshop to discuss fundamental aspects of experimental design of research using animals and animal models, aimed at improving reproducibility.  The workshop will include invited speakers to provide background and context on how to ensure that animal studies are of sufficient quality and relevance, and described in adequate detail for the findings to provide an evidence base for any decision to proceed into clinical trials or other outcomes of public importance.  The ad hoc committee will develop a workshop agenda, select and invite speakers and discussants, and moderate the workshop discussions.  An individually-authored summary of the presentations and discussions at the workshop will be prepared by a designated rapporteur in accordance with institutional guidelines.

This workshop was made possible by generous donations from:

Covance Laboratories, Inc., University of Washington, University of Michigan, Massachusetts Institute of Technology, Novartis Corporation, American Veterinary Medical Association, American College of Laboratory Animal Medicine, Massachusetts General Hospital, GlaxoSmithKline, University of California–Davis, University of Illinois, Charles River Laboratories, Bayer Healthcare, Merck, Janssen Pharmaceutical Companies of Johnson and Johnson and the National Academies.

Reproducibility Issues in Research with Animals and Animal Models Workshop Committee

Kent Lloyd, Co-Chair
University of California, Davis
Steven Niemi, Co-Chair
American College of Laboratory Animal Medicine
Bonnie V. Beaver
Texas A&M University
Brian R. Berridge
Pamela Chamberlain
U.S. Food and Drug Administration
Carol Clarke
APHIS – US Department of Agriculture
Margaret S. Landi
Malcolm Macleod
University of Edinburgh, UK
Brian C. Martinson
HealthPartners Institute for Education and Research
Susan Brust Silk
Office of Laboratory Animal Welfare
National Institutes of Health