IACUC Issues Associated with Zebrafish

George E. Sanders

George E. Sanders, DVM, MS, Certified Fish Pathologist (AFS/FHS), is a lecturer and Aquatic Animal Program Director in the Department of Comparative Medicine in the School of Medicine at the University of Washington and is the Veterinary Medical Officer of the US Geological Survey’s Western Fisheries Research Center in Seattle.

Address correspondence and reprint requests to Dr. George E. Sanders, Department of Comparative Medicine, University of Washington School of Medicine, Health Science Center Box 357190, Seattle, WA 98195-7190 or email gsander@uw.edu.

Abstract

The articles in this issue review pertinent and specific information about infectious and noninfectious disease, housing system design and function, husbandry practices and techniques, and Internet resources as they specifically relate to zebrafish (Danio rerio). This article explores aspects that members of institutional animal care and use committees, husbandry care staff, physical plant personnel, veterinarians, principal investigators, and research personnel should consider with regard to the appropriate and necessary care and use of this unique fish model in a teaching, laboratory, or research setting. This information is designed to enhance understanding and facilitate collegial discussions to inform decision making about zebrafish care and use at various institutions or facilities.

Key Words: Danio rerio; disease; housing systems; husbandry and care; institutional animal care and use committee (IACUC); resources; zebrafish

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